FBI Assistant Director Walter Skinner is the prime suspect in a homicide involving a woman he was with the night of her death. Mulder and Scully are all he has to prove his innocence, as superior officers try to shut him down and the only clue is a mysterious old woman.
就在這個節(jié)眼上，環(huán)世界進(jìn)行研究神奇法動物之動的魔法物學(xué)家紐（埃迪·德梅恩 Eddie Redmayne 飾）抵達(dá)了約，他隨攜帶的魔手提箱里裝著幾十他一路營的魔法動們，而他一舉一動均處于隸于魔法部前傲羅蒂（凱瑟?沃特森 Katherine Waterston 飾）的監(jiān)視下。一場外中，麻雅各布（·福格勒 Dan Fogler 飾）誤拿了紐特的提箱，并放出了藏箱子里的法動物，此，紐特蒂娜、雅布和蒂娜妹妹奎妮艾莉森·朵兒 Alison Sudol 飾）不得不踏上了找魔法動的旅途?